By John R. Evans M.D., D.Phil. (Oxon.), F.A.C.P., F.R.C.P.(C) (auth.), John O. Godden M.D., C.M., M.Sc.(Med.), F.R.C.P.(C), M.A.(Educ. Th.) (eds.)
Viewed as contributions to carrying on with clinical schooling, many clinical conferences disappoint simply because, even though software committees plan with care, compile very good college and divulge them to their friends, to different physicians and to accommodate employees. the impact is evanescent. conferences dissipate a lot specialist time and public money to stimulate the fairly few who attend. for that reason the dictum "Hold a symposium and succeed in a number of hundred; flow a complaints and achieve the area. " regardless of this dictum, many organizers of medical conferences turn away from the e-book of court cases. insisting that lecturers won't take part in the event that they need to organize publishable manuscripts and, in the event that they do conform to organize them, will hold up for months or, every so often, won't come via in any respect. notwithstanding, this is an issue of association and resolution: e. g . . a few software chairmen make the check of charges and honoraria contingent upon receipt of a publishable manuscript. Cox and his colleagues in Australia went one greater: they prepared the 1st overseas melanoma convention in Sydney in November 1972 and released a two-volume court cases ("Melanoma and pores and skin melanoma" and 'The Nature of Leukemia") sooner than the conferences started. As Dr. Cox notes, "This preprinting of the total papers freed each one speaker from the need of recounting huge amounts of information in order that every one paper should be opened extra quickly and provocatively after which defended in dialogue" (Report of the foreign melanoma convention, Med J an inventory, I: 12-33, June 24, 1972).
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F. K. (C)* The tumor registry at the Hospital for Sick Children (HSC) from 1924 to 1972 lists 43 renal tumors which presented when the patient was less than one year of age. Of the six tumors that presented in the neonatal period (when the patient was less than one month of age), five belonged to the entity known variously as fetal mesodermal hamartoma (FMH), congenital mesoblastic nephroma, or leiomyoma of the kidney. The five patients with FMH are all alive, free of tumor and have had follow-up studies made at periods ranging from 19 months to 13 years.
NO RT. R A N D o FAILURE OR Regimen A. RT + VCR Regimen B. RT + VCR + AMD Regimen A. RT + VCR Regimen B. RT + VCR + AMD Regimen A. RT + AMD Regimen B. RT + AMD + VCR OFF STUDY. RT = Radiotherapy AMD Actinomycin-D Fig. 1. Organization of the Wilms' Tumor Study. 51 VCR = Vincristine RESULTS Since the inception of the Study in October 1969, more than 300 patients have been enrolled. The data are too fragmentary to permit conclusions regarding the efficacy of any of the study regimens, but we have no evidence to indicate that the omission of radiation therapy in Group I has adversely affected results.
Which of the two chemotherapeutic agents known to be effective against Wilms' tumor gives the better result; and can this result be improved by their combined use? As secondary objectives, the Study sought to understand better the neoplasm and the neoplastic process through careful pathologic evaluation of the specimen both grossly and histologically; and by obtaining epidemiological data regarding possible associated diseases in the patients and in their families. All patients are placed in specific groups according to the extent of their disease determined by individual clinical, roentgen and pathologic evaluation.