By Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Content material: the fundamental rules of GRID / Peter Goodford -- Calculation and alertness of molecular interplay fields / Rebecca C. Wade -- Protein selectivity reviews utilizing GRID-MIFs / Thomas Fox -- FLAP: 4-point pharmacophore fingerprints from GRID / Francesca Perrucio ... [et al.] -- The complexity of molecular interplay: molecular form fingerprints by means of the PathFinder procedure / Iain McLay ... [et al.] -- Alignment-independent descriptors from molecular interplay fields / Manuel Pastor -- 3D-QSAR utilizing the GRID/GOLPE strategy / Wolfgang Sippl -- Use of MIF-based VolSurf descriptors in physicochemical and pharmacokinetic reviews / Raimund Mannhold ... [et al.] -- Molecular interplay fields in ADME and protection / Giovanni Cianchetta ... [et al.] -- growth in ADME prediction utilizing GRID-molecular interplay fields / Ismael Zamora ... [et al.] -- swift ADME filters for lead discovery / Tudor I. Oprea ... [et al.] -- GRID-derived molecular interplay fields for predicting the location of metabolism in human cytochromes / Gabriele Cruciani ... [et al.]
By Guodong Chen
The ebook highlights the present practices and destiny developments in structural characterization of impurities and degradants. It starts off with an summary of mass spectrometry concepts as relating to the research of impurities and degradants, by way of experiences regarding characterization of technique comparable impurities (including strength genotoxic impurities), and excipient similar impurities in formulated products. either normal practitioners in pharmaceutical learn and experts in analytical chemistry box will reap the benefits of this ebook that might aspect step by step techniques and new suggestions to unravel tough difficulties regarding pharmaceutical research.
Quality: Vector, Searchable, no longer bookmarked
By Mary Fieser
Other volumes within the series
Reagents for natural Synthesis, quantity 1
"...well so that it will changing into the reference of selection for everybody inquisitive about concepts of synthesis in natural chemistry."
"Due to the book’s unheard of insurance of reagents and their makes use of, the providers part, the well-organized indexes, and the convenience of finding info both within the reagents part or in a single of the indexes, i might give some thought to this publication a worthwhile addition to the library of each collage of pharmacy. i might additionally suggest that graduate scholars collect this precious reference publication for his or her personal own library."
—Richard H. Hammer, college of Florida 1967 1,457 pp.
Reagents for natural Synthesis, quantity 2
"The Fiesers' moment quantity updates, revises, and provides immensely to the content material and price in their first compilation of natural reagents. the necessity for a series of handbooks equivalent to the Fiesers have supplied has lengthy been famous, and the authors' virtually conventional organization with, willing expertise of, and curiosity within the distinct strategies of natural chemistry make the interpreting and research of those works in particular worthwhile."
—Journal of the yankee Chemical Society, 1969 538 pp.
Reagents for natural Synthesis, quantity 3
"This quantity, in addition to the former ones, is intensely helpful to an artificial natural chemist. All 3 volumes can be in his library."
—American magazine of Pharmaceutical Education, 1972 401 pp.
Reagents for natural Synthesis, quantity 4
"Synthetic chemists have stumbled on the 1st 3 volumes of the Fiesers' Reagents for natural Synthesis very priceless and should welcome the hot fourth quantity of this series.... As ahead of, the authors have rigorously culled the new (1970–1972) literature for purposes of natural, inorganic, and organometallic reagents, outdated and new, and current them alphabetically in accordance with reagent.... not just are their purposes in synthesis mentioned, yet necessary tricks, with references, relating their instruction or advertisement providers are given. the unreal chemist will locate this quantity a veritable gold mine of necessary information."
—Journal of Organometallic Chemistry, 1974 660 pp.
Reagents for natural Synthesis, quantity 5
"New reagents for natural synthesis play a really vital position within the armentarium of the sensible natural chemist. it's, for this reason, now not staggering that this wonderful sequence via Mary and Louis Fieser is a bestseller and a "must" for the house library.... The Fiesers have performed it back. an outstanding quantity that may be heartily recommended."
—Pharmaceutical Journal, 1975 864 pp.
Reagents for natural Synthesis, quantity 6 1977 765 pp.
By Scott E. Denmark
For all volumes: the volumes of natural Reactions are collections of chapters every one dedicated to a unmarried response or a definitive part of a response, of extensive applicability. The authors have had event with the techniques surveyed. the themes are awarded from the preparative perspective and specific recognition is given to obstacles, interfering impacts, results of constitution and the choice of experimental recommendations. every one bankruptcy contains numerous unique techniques illustrating the numerous transformations of the tactic. every one bankruptcy includes drugs that come with all of the examples of the response into account that the writer has been capable of finding.
By René P. Schwarzenbach, Philip M. Gschwend, Dieter M. Imboden
Environmental natural Chemistry makes a speciality of environmental elements that govern the approaches that ensure the destiny of natural chemical compounds in common and engineered structures. the data came upon is then utilized to quantitatively assessing the environmental behaviour of natural chemical compounds. Now in its second variation this e-book takes a extra holistic view on physical-chemical houses of natural compounds. It contains new issues that handle elements of gas/solid partitioning, bioaccumulation, and modifications within the surroundings. * buildings chapters into simple and complex sections* comprises illustrative examples, difficulties and case reports* Examines the basic facets of natural, actual and inorganic chemistry - utilized to environmentally correct difficulties* Addresses difficulties and case stories in a single volume
Quality: top of the range experiment, Searchable, Bookmarked
By A.C. Knipe, William Edward Watts
This quantity is the 38th during this classical sequence. In each quantity the content material is split within the assorted periods of natural response mechanisms:
An skilled staff of authors is compiling those reports each year, in order that the reader can depend upon a continual caliber of choice and presentation. As a brand new carrier to the reader all response mechanisms resulting in stereospecific items are highlighted. This displays the wishes of the natural man made group with ends up in chiral reactions.
distinct writer and topic indexes support the reader to discover the knowledge they're searching for.
By Houben J., Weyl T.
Methoden der Organischen Chemie (Methods of natural Chemistry, referred to as Houben-Weyl) is a typical reference paintings for chemists engaged in natural synthesis. In volumes on compound periods, together with all Supplemental volumes, preparative tools are taken care of comprehensively and seriously. Tables of examples evaluate crucial equipment and convey their scope. unique experimental systems are given for the simplest equipment. The reactivity and additional reactions of every compound classification also are awarded. The huge use of formulation schemes assist in making the German-language volumes extra with ease comprehensible to non-German readers.
By Maurizio Canavari, Kent D. Olson
The booklet provides an summary of the natural nutrients area, either in Italy and within the US. It covers monetary concerns raised by means of natural farming, making an allowance for the consumer's wishes but additionally the managerial and funds constraints skilled by means of the farmers. The e-book additionally info how agricultural economists practice analyses facing natural produce at various issues within the offer chain.