By T ed. Wiegel
During the last few years, great development has been made within the improvement of remedies for prostate and bladder melanoma. accordingly, drastically enhanced surgical strategies in addition to new different types of radiotherapy, chemotherapy and hormonal treatment are actually to be had. This interdisciplinary method is mirrored within the vast scope of this quantity, which goals to supply an summary of present remedy options for bladder and prostate melanoma. the 1st a part of the booklet discusses the optimization of radiation concepts like 3D making plans or IMRT and specializes in definitive radiotherapy without or with adjuvant or neoadjuvant hormonal manipulation. the standard of lifestyles after treatment is one other very important factor. extra chapters take care of radical cystectomy and organ upkeep through radio-chemotherapy in addition to the therapy of T1G3 melanoma. within the final half, the emphasis lies on brachytherapy, which has develop into more and more very important for the therapy of prostate melanoma.
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Extra resources for Controversies in Uro-Oncology: 5th International Symposium on Special Aspects of Radiotherapy, Berlin, Germany, May 11-13, 2000 (Frontiers of Radiation Therapy & Oncology)
Link P, Freiha FS, Stamey TA: Adjuvant radiation therapy in patients with detectable prostatespecific antigen following radical prostatectomy. J Urol 1991;145:532–534. Morgan WR, Bergstrahl EJ, Zincke H: Long-term evaluation of radical prostatectomy as treatment for clinical stage C (T3) prostate cancer. Urology 1993;41:116–120. Morris MM, Dallow KC, Zietman AL, Park J, Althausen A, Heney NM, Shipley WU: Adjuvant and salvage irradiation following radical prostatectomy for prostate cancer. Int J Radiat Oncol Biol Phys 1997;38:731–736.
Mohan DS, Kupelian PA, Willoughby TR: Shourt-course intensity-modulated radiotherapy for localized prostate cancer with daily transabdominal ultrasound localization of the prostate gland. Int J Radiat Oncol Biol Phys 2000;46:575–580. Planning Target Volume Definition in Dose-Escalation Studies 23 22 23 24 25 26 27 28 29 30 31 32 33 Lattanzi J, McNeely S, Hanlon A, Schultheiss TE, Hanks GE: Ultrasound-based stereotactic guidance of precision conformal external beam radiation therapy in clinically localized prostate cancer.
2) In 7 cases PSA unknown. Results of RT in Patients with PSA Elevation Out of the Undetectable Range or Persisting PSA after RP A significant proportion of the increased PSA levels can be reduced into the undetectable range again by RT. The results vary between 30 and 70% depending on patient selection [4, 6, 14, 18, 28, 29] (table 1). 2 ng/ml after RT in 133/239 patients (55%) [4, 6, 12, 14, 28]. The study groups under Coezee , Forman , Link , and Morris  obtained concurring results, showing 64–69% of the patients with PSA levels decreasing again into the undetectable range.