By David P. Rose (auth.), Elizabeth K. Weisburger (eds.)
The fourth annual American Institute for melanoma study (AICR) convention on nutrition, foodstuff and melanoma used to be held on the L'Enfant Plaza inn in Washington, D. C. , September 2~3, 1993. in response to current matters and in keeping with present tendencies, the subject matter was once "Diet and Breast melanoma. " This court cases quantity is made from chapters from the platform displays of the 2 day convention and abstracts from the poster consultation held on the finish of the 1st day. Experimentally, there's adequate proof to aid a dating among nutritional fats and the danger of breast melanoma. A meta-analysis used to be supplied through information from 114 experiments with over 10,000 animals, divided into teams fed advert libitum on diets with assorted degrees or assets of fats, or assorted degrees of power limit. This workout prompt that linoleic acid was once an immense determinant of mammary tumor improvement yet that different fatty acids additionally better mammary tumor improvement in animals. even though, as pointed out through numerous audio system, effects from epidemiological experiences usually are conflicting, hence resulting in confusion between either well-being pros and the general public. Surveys of particular populations that have migrated from international locations with low breast melanoma premiums to these with better premiums are usually probably the most compelling reviews with admire to a excessive fats diet-breast melanoma organization. still, a variety of cohort and potential stories, a few really huge, didn't seem to convey a courting among intake of fats (any kind) and breast cancer.
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Extra resources for Diet and Breast Cancer
The disease is more common in North America, Australia and Western Europe, relative to South and Central America, Asia and Africa. 1-3 Epidemiologic studies which relate per capita consumption of various dietary constituents to international variations in breast cancer incidence provide the most consistent evidence for an association between diet and breast cancer. 4-7 A significant positive association between total fat consumption and breast cancer incidence or mortality was found in all seven studies in which total dietary fat was reported.
M. Yuan, K. Katsouyanni, E Lubin, E. Marubini, B. Modan, T. Rohan, P. Toniolo, and Y. Shunzhang, Dietary factors and risk of breast cancer: combined analysis of 12 case-control studies, 1. Natl. Cancer Inst. 82:561 (1990). 18. A. D. L. G. A. Kaye, and AR. Folson, Dietary fat and postmenopausal breast cancer, J. Natl. Cancer Inst. 84:1092 (1992). Diet and Breast Cancer 33 19. M. Friedenreich, M. B. Miller, A cohort study of fat intake and risk of breast cancer, J. Natl. Cancer Inst. 83:336 (1991).
Importantly, the international correlational analyses are supported qualitatively by the results of animal feeding trials, including the finding of a possible substantial role for polyunsaturated fat consumption2 (see also the contribution by Freedman and Clifford in this volume). The second interpretation argues 6 that "the totality of evidence does not support the judgment of a causal association" between fat consumption and postmenopausal breast cancer risk. ,,6 Counter arguments can be presented to each of these viewpoints.