By M.D. Hauser, L. Young (auth.), Donald W. Pfaff, Claude Kordon, Philippe Chanson, Yves Christen (eds.)
Advances in twenty first Century neuroscience and endocrinology will let advanced difficulties of drugs and public healthiness to be elucidated. between those difficulties are disasters of ordinary social and sexual behaviors. because it seems, those behaviors are encouraged via hormone activities within the human mind utilizing mechanisms that we have got inherited from reduce animals. This e-book concentrates on significant themes: First, the molecular and neural biology of hormone activities proper to basic social behaviors; and moment, the scientific remedy of human sufferers in whom those behaviors have long past wrong.
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Additional info for Hormones and Social Behaviour
The fusiform face area: a module in human extrastriate cortex specialized for face perception. J Neurosci 17:4302–4311 Kirsch P, Esslinger C, Chen Q, Mier D, Lis S, Siddhanti S, Gruppe H, Mattay VS, Gallhofer B, meyer-Linderberg A. (2005) Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci 5:11489–11493 Landgraf R, Neumann I (2004) Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication.
Because excellent reviews exist concerning the role of central dopamine and central 5-HT in sexual behavior (Waldinger and Olivier 1998b; Olivier et al. 1998; Bitran and Hull 1987; Melis and Argiolas 1995; Hull et al. 1999, 2004), here we only brieﬂy review the most important ﬁndings with regard to the role of serotonin in the regulation of sexual behavior of male mammals, with focus on the male rat (for extensive reviews, see Waldinger et al. 1998; Olivier et al. 1998; De Jong et al. 2006). Animal Sexual Behavior Increasing understanding of the neurobiology of normal and “pathological” sexual functioning has been derived from animal studies in which speciﬁc brain areas have been manipulated or animals have been challenged pharmacologically (for reviews, see Larsson and Ahlenius 1999; Pfaus 1999).
2003). Apparently, normal offensive aggression is positively related to serotonergic neuronal activity, whereas an inverse relationship probably exists between 5-HT activity and impulse-like violent aggression (Coccaro 1989). Thus a general pattern emerges where trait and state aggression are probably differentially regulated by the 5-HT system, although much more research is needed to substantiate this hypothesis (for recent discussion, see Ferrari et al. 2005). 30 B. W. D. Waldinger 5-HT Receptors The 14 different 5-HT receptors and the 5-HTT enable the unraveling of the function and contribution of the different receptors in various aspects of aggression.