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Download IASLC Textbook of Prevention and Early Detection of Lung by Hirsch R. PDF

By Hirsch R.

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Example text

In addition to modeling putative major gene effects, the model simultaneously estimated effects attributed to pack years of cigarette smoking. Using their model, different profiles of genetic and environmental exposure characterize lung cancer cases at various ages. Seventy-one percent of lung cancer cases younger than 50 years of age were at least partially attributable to an underlying genetic susceptibility; by age 70, 72% of lung cancers are attributable to smoking alone. 7) increased risk in the 40- to 59-year-old age group.

Steenland K, Stayner L, Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997; 8:491–503. 41. International Agency for Research on Cancer (IARC), Chromium, nickel and welding. IARC Monographs on the evaluation of carcinogenic risk to humans, Volume 49. IARC, Lyon, 1990. 42. Grimsrud TK, Berge SR, Haldorsen T, Andersen A, Exposure to different forms of nickel and risk of lung cancer. Am J Epidemiol 2002; 156:1123–32. 43. Hopenhayn-Rich C, Biggs ML, Smith AH, Lung and kidney cancer mortality associated with arsenic in drinking water in Cordoba, Argentina.

Am J Epidemiol 2002; 155:1016–22. 57. Liddell FDK, The interaction of asbestos and smoking in lung cancer. Ann Occup Hyg 2001; 45:341–56. 58. Liddell FDK, Joint action of smoking and asbestos exposure on lung cancer. Occup Environ Med 2002; 59:494–5. 59. Pershagen G, Akerblom G, Axelson O, Clavensjo B, Damber L, Residential radon exposure and lung cancer in Sweden. N Engl J Med 1994; 330:159–64. 60. Committee of the Biological Effects of Ionizing Radiation, Health effects on exposure to low levels of radon.

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