MFV3D Book Archive > Organic Chemistry > Download Modern Solvents in Organic Synthesis by Paul Knochel, J. Auge, B. Betzemeier, B. Cornils, D.P. PDF

Download Modern Solvents in Organic Synthesis by Paul Knochel, J. Auge, B. Betzemeier, B. Cornils, D.P. PDF

By Paul Knochel, J. Auge, B. Betzemeier, B. Cornils, D.P. Curran, P. Knochel, W. Leitner, B. Linclau, A. Loupy, A. Lubineau, J. Maul, P.J. Ostrowski, D. Sinou, G.A. Ublacker

This quantity covers using glossy solvent platforms for the functionality of extra effective, selective and comparatively cheap natural differences. over the last twenty years, water has emerged as a brand new necessary response media for the functionality of natural or steel catalyzed reactions. extra lately, different response media resembling perfluorinated solvents or supercritical CO2 have confirmed their software for lots of natural syntheses in addition to in combinatorial chemistry. the main consultant business purposes of a few of those smooth solvent structures are defined, and the factitious possibilites of acting natural reactions within the absence of solvents tested.

Show description

Read Online or Download Modern Solvents in Organic Synthesis PDF

Best organic chemistry books

World of Carbon

Introducing Carbon—and the basics of natural chemistry

Chemists divide all ingredients into sessions. in a single classification are things like olive oil, sugar, starch, glue, gelatin, silk, rubber, paper, and penicillin. those are examples of natural elements. within the different type are things like air, water, sand, clay, salt, gold, silver, iron, brass, glass, and urban. those are examples of inorganic elements. the excellence among the 2 emerged whilst it turned obtrusive that natural ingredients are made of molecules that nearly consistently contained at the very least one carbon atom; it then turned handy to name any substance with carbon atoms in its molecule natural and any substance with no carbon atoms inorganic. during this means the area of natural chemistry got here to be pointed out with the realm of carbon.

In the realm of Carbon, Isaac Asimov, introducing the research of natural chemistry, bargains a transparent, shiny, and understandable research of a few of the most typical natural compounds in our global. And he demonstrates how elevated wisdom of the constitution of those carbon compounds—from anaesthetics and antifreeze to color and perfume—has ended in a greater existence for all of us.

Those universal natural compounds no longer mentioned during this quantity are coated by means of Dr. Asimov in a better half quantity that concentrates on carbon compounds containing at the least one atom of nitrogen. safely entitled the area of Nitrogen, it's also on hand in Collier Books.

Organic Syntheses Bsaed on Name Reactions and Unnamed Reaction

Synthetically worthwhile natural reactions or reagents are frequently pointed out through the identify of the discoverer(s) or developer(s). Older identify reactions are defined in textual content books, yet extra lately constructed synthetically worthy reactions that could were linked sometimes with a reputation will not be constantly renowned.

Organic Synthesis Highlights

This strange selection of forty nine essays offers an outline of the tendencies and accomplishments of artificial natural chemistry in recent times. precise in its process, it bargains with virtually each element of contemporary synthesis. the 1st a part of the publication describes equipment and reagents, with specific emphasis on speedily constructing organometallic and biooriented methods.

Organic Synthesis: The Disconnection Approach

One method of natural synthesis is retrosynthetic research. With this process a chemist will begin with the constitution in their aim molecule and gradually reduce bonds to create less complicated molecules. Reversing this strategy provides a man-made path to the objective molecule from easier beginning fabrics.

Extra resources for Modern Solvents in Organic Synthesis

Example text

56 Topics in Current Chemistry, Vol. 206 © Springer-Verlag Berlin Heidelberg 1999 42 D. Sinou List of Abbreviations BDPP Binap Binas-Na 2,4-bis(diphenylphosphino)pentane 2,2¢-bis(diphenylphosphino)-1,1¢-binaphthalene octasodium salt of 2,2¢-bis[(m-sulfonatodiphenylphosphino)methyl]-4,4¢,8,8¢-tetrasulfonato-1,1¢-binaphthalene Bisbis-Na hexasodium salt of 2,2¢-bis[(m-sulfonatodiphenylphosphino)methyl]-disulfonato-1,1¢-biphenyl CBD 1,2-bis[(diphenylphosphino)methyl]cyclobutane Chiraphos 2,3-bis(diphenylphosphino)butane dppp 1,3-bis(diphenylphosphino)propane Norbos-Na trisodium salt of 3,4-dimethyl-2,5,6-tris(p-sulfonatophenyl)1-phosphanorborna-2,5-diene PPM 4-diphenylphosphino-2-(diphenylphinomethyl)pyrrolidine PTA 1,3,5-triaza-7-phosphaadamantane tppms sodium salt of m-sulfonatophenyldiphenylphosphine tppts trisodium salt of tris(m-sulfonatophenyl)phosphine 1 Introduction Homogeneous organometallic catalysis is now a well-used tool in organic synthesis, probably due to the high activities and selectivities generally achieved under mild reaction conditions.

43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 57 Bakos J, Karaivanov R, Laghmari M, Sinou D (1994) Organometallics 13:2951 Joò F, Csiba P, Bènyei A (1993) J Chem Soc Chem Commun 1602 Bergbreiter DE, Liu Y-S (1997) Tetrahedron Lett 38:3703 Amrani Y, Lecomte L, Sinou D, Bakos J, Toth I, Heil B (1989) Organometallics 8:542 Laghmari M, Sinou D, Masdeu A, Claver C (1992) J Organomet Chem 438:213 Toth I, Hanson BE, Davis ME (1990) Cat Lett 5:183 Tòth I, Hanson BE (1990) Tetrahedron: Asymmetry 1:895 Toth I, Hanson BE (1990) Tetrahedron: Asymmetry 1:913 Tòth I, Hanson BE, Davies ME (1990) J Organomet Chem 396:363 Wan KT, Davis ME (1994) J Catal 148:1 Wan KT, Davis ME (1993) J Chem Soc Chem Commun 1262 Wan KT, Davis ME (1993) Tetrahedron: Asymmetry 4:2461 Wan KT, Davis ME (1994) Nature 370:449 Wan KT, Davis ME (1995) J Catal 152:25 Ding H, Hanson BE, Bakos J (1995) Angew Chem Int Ed Engl 34:1645 Kumar A, Oehme G, Roque JP, Schwarze M, Selke E (1994) Angew Chem Int Ed Engl 33:2197 Flach HN, Grassert Y, Oehme G (1994) Macromol Chem Phys 195:3289 Grassert I, Paetzolt E, Oehme G (1993) Tetrahedron 49:6605 Malmström T, Anderson C (1996) J Chem Soc Chem Commun 1135 Bakos J, Orosz A, Heil B, Laghmari M, Lhoste P, Sinou D (1991) J Chem Soc Chem Commun 1684 Lensink C, De Vries JG (1992) Tetrahedron: Asymmetry 3:235 Bènyei A, Joò F (1990) J Mol Catal 58:151 Darensbourg DJ, Joò F, Kannisto M, Kathò A, Reibenspies JH (1992) Organometallics 11:1990 Darensbourg DJ, Joò F, Kannisto M, Kathò A, Reibenspies JH, Daigle DJ (1994) Inorg Chem 33:200 Darensbourg DJ, Stafford NW, Joò F, Reibenspies JH (1995) J Organomet Chem 488:99 Sinou D, Safi M, Claver C, Masdeu A (1991) J Mol Catal 68:L9 Cornils B, Kuntz EG (1995) J Organomet Chem 502:177 Cornils B, Wiebus E (1995) CHEMTECH 33 Herrmann WA, Kohlpaintner CW, Bahrman H, Konkol W (1992) J Mol Catal 73:191 Herrmann WA, Kohlpaintner CW, Manetsberger RB, Bahrman H, Kottmann H (1995) J Mol Catal A 97:65 Cornils B, Wiebus E (1996) Recl Trav Chim Pays-Bas 115:211 Eckl RW, Priermeier T, Herrmann WA (1997) J Organomet Chem 532:243 Bartik T, Bunn BB, Bartik B, Hanson BE (1994) Inorg Chem 33:164 Russell MJH (1988) Platinum Met Rev 32:179 Fell B, Papadogianakis G (1991) J Mol Catal 66:143 Ding H, Hanson BE, Bartik T, Bartik B (1994) Organometallics 13:3761 Bartik T, Bartik B, Hanson BE (1994) J Mol Catal 88:43 Bartik T, Bartik B, Guo I, Hanson BE (1994) J Organomet Chem 480:15 Ding H, Hanson BE (1994) J Chem Soc Chem Commun 2747 Bartik T, Ding H, Bartik B, Hanson BE (1995) J Mol Catal A 98:117 Stössel P, Mayer HA, Auer F (1998) Eur J Inorg Chem 37 Chaudhari RV, Bhanage BM, Desplande RM, Delmas H (1995) Nature 373:501 Monflier E, Tilloy S, Fremy G, Castanet Y, Mortreux A (1995) Tetrahedron Lett 36:9481 Monflier E, Fremy G, Castanet Y, Mortreux A (1995) Angew Chem Int Ed Engl 34:2269 Arhancet JP, Davis ME, Merola JS, Hanson BE (1989) Nature 339:454 Arhancet JP, Davis ME, Merola JS, Hanson BE (1990) J Catal 121:327 Horvath IT (1990) Catal Lett 6:43 Arhancet JP, Davis ME, Hanson BE (1991) J Catal 129:100 Fremy E, Monflier E, Carpentier JF, Castanet Y, Mortreux A (1995) Angew Chem Int Ed Engl 34:1474 58 72.

Chapman & Hall, London, chap 1 Otto S, Boccaletti G, Engberts JBFN (1998) J Am Chem Soc 120:4238 Larsen SD, Grieco PA (1985) J Am Chem Soc 107:1768 Grieco PA, Larsen SD (1986) J Org Chem 51:3553 Grieco PA, Parker DT (1988) J Org Chem 53:3658 Waldmann H (1988) Angew Chem Int Ed Engl 27:274 Waldmann H, Braun M (1991) Liebigs Ann Chem 1045 Parker DT (1998) Hetero-Diels-Alders reactions. In:Grieco PA (ed) Organic synthesis in water. Chapman & Hall, London, chap 2 Yu L, Chen D, Wang PG (1996) Tetrahedron Lett 37:2169 Yu L, Li J, Ramirez J, Chen D, Wang PG (1997) J Org Chem 62:903 Grieco PA, Bahsas A (1987) J Org Chem 52:5746 Lubineau A, Augé J, Lubin N (1991) Tetrahedron Lett 32:7529 Lubineau A, Augé J, Grand E, Lubin N (1994) Tetrahedron Lett 50:10265 Grieco PA, Henry KJ, Nunes JJ, Matt Jr JE (1992) J Chem Soc Chem Commun 368 Mackeith RA, McCague R, Olivo HF, Palmer CF, Roberts SM (1993) J Chem Soc Perkin Trans 1 313 McCague R, Olivo HF, Roberts SM (1993) Tetrahedron Lett 34:3785 Burlina F, Favre A, Fourrey J-L, Thomas M (1997) Bio & Med Chem Lett 7:247 Lubineau A, Augé J, Lubin N (1993) Tetrahedron 49:4639 Lubineau A, Queneau Y (1995) J Carbohydrate Chem 14:1295 (a) Dignam KJ, Hegarty AF, Quain PL (1978) J Org Chem 43:388; (b) Inoue Y, Araki K, Shiraishi S (1991) Bull Chem Soc Jpn 64:3079 Wijnen JW, Steiner RA, Engberts JBFN (1995) Tetrahedron Lett 36:5389 Pandey PS, Pandey IK (1997) Tetrahedron Lett 38:7237 Lubineau A, Bouchain G, Queneau Y (1995) J Chem Soc Perkin Trans 1 2433 Magnier E, Langlois Y (1998) Tetrahedron Lett 39:837 Lubineau A, Bouchain G (1997) Tetrahedron Lett 38:8031 Takaya H, Makino S, Hayakawa Y, Noyori R (1978) J Am Chem Soc 100:1765 Copley SD, Knowles JR (1987) J Am Chem Soc 109:5008 White WN, Wolfarth EF (1970) J Org Chem 35:2196 Coates RM, Rogers BD, Hobbs SJ, Peck DR, Curran DP (1987) J Am Chem Soc 109:1160 Brandes E, Grieco PA, Gajewski JJ (1989) J Org Chem 54:515 Water as Solvent in Organic Synthesis 37 87.

Download PDF sample

Rated 4.36 of 5 – based on 32 votes