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Download Multiple Primary Malignant Neoplasms: The Connecticut by Bruce S. Schoenberg PDF

By Bruce S. Schoenberg

When requested why he robbed banks, an astute and good fortune­ ful felony is expounded to have spoke back "Because that is the place the cash is kept." Why examine sufferers with a number of basic cancers? the reply follows an identical functional technique. as the extensive research of such sufferers is particularly prone to yield information valuable to either the medical and examine on­ cologist. reviews of this challenge supply a right away go back for the clinician answerable for the care of melanoma sufferers. With better different types of remedy, those everyone is having fun with longer sessions of survival. One vital think about retaining elevated survival is the early detection and remedy of recent fundamental tumors that can increase. Analyses of a number of basic malignancies function a consultant to the possible anatomic position of a next basic and support outline features of the person at excessive chance for a number of basic melanoma. yet simply as therapy may well increase the lifetime of the melanoma sufferer, it will probably additionally bring up the chance of a next malignancy. stories of a number of primaries offer a good capability for quantifying almost certainly damaging results of present healing modalities.

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1969). The excess was not statistically significant. The close anatomic proximity of the colon and urinary tract necessitates careful study to distinguish primary and metastatic lesions. For the Connecticut patients with malignancies of both the large intestine and urinary tract, the two neoplasms were microscopically verified in slightly over 85% of the cases. With regard to deficiencies of observed-over-expected second primary cancers, those involving the same organ are artifactual. For example, as a treatment for cancer of the stomach or rectum, the entire organ is often removed surgically and the patient is no longer at risk for developing a subsequent cancer of this same organ.

Tongue -----------------. Mouth ------------------. Mouth ------------------. Mouth ------------------. Pharynx ----------------. Pharynx ----------------. Pharynx ----------------. Esophagus Lung/bronchus Other respiratory Esophagus Nose and sinuses Larynx Lung/bronchus Esophagus Stomach Lung/bronchus C. In organs apparently unrelated structurally or functionally Salivary gland ---------. Breast Table 21. Common metastatic sites for primary malignant tumors of the buccal cavity and pharynx (HOLLAND and FREI, 1973; WILLIS, 1973; RUBIN, 1974) Anatomic location of the primary malignant tumor Common metastatic sites Lip and oral cavity Submental, facial, and cervical lymph nodes; mandible; liver; lung; base of skull and cranial nerves Salivary glands Lung; middle ear; base of brain 46 Chapter 7 Index Tumors of the Digestive System Population Studied.

09 3. 0 1. 44 2. C c. 1:5 1. 01 1. 33 O. 19 O. 0 O. 53* OBS/EXP Table 8. 5 5 7 7 MOUTH PHARYNX ESOPHAGUS 0 0 c. 68 OES/EXP 922. 0 Neither tumor microscopically confirmed % No. 1 2 1 e oes 0 Only 2nd tumor microscopically confirmed % No. 0 Only 1st tumor microscopically confirmed % No. 2 Q 3 Q aBS YEARS> 5 NUMBER OF PERSONS= PERSON-YRS OF 2 Both tumors microscopically confirmed % No. C < YEARS TOTAL TONGUE Table 10. Histologic confirmation of multiple primary malignancies TONG U E MOUTH PHARYNX ESOPHAGUS SUBSEQUENT PFIMARY STHS FIRST Table 9.

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