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Download Organic Chemistry (2nd Edition) by Stuart Warren, Jonathan Clayden, Nick Greeves PDF

By Stuart Warren, Jonathan Clayden, Nick Greeves

Inspiring and motivating scholars from the instant it released, natural Chemistry has proven itself in precisely one version because the student's selection of an natural chemistry text.

The second edition refines and refocuses natural Chemistry to supply a textual content that's much more student-friendly, coherent, and logical in its presentation than before.

Like the 1st, the second one variation is equipped on 3 principles:
• An explanatory strategy, in which the reader is influenced to appreciate the topic and never simply research the facts;
• A mechanistic technique, giving the reader the ability to appreciate compounds and reactions by no means formerly encountered;
• An evidence-based technique, commencing basically how and why reactions occur as they do, giving additional intensity to the reader's understanding.

The authors write basically and without delay, sharing with the reader their very own fascination with the topic, and major them rigorously from subject to subject. Their sincere and open narrative flags pitfalls and misconceptions, guiding the reader in the direction of a whole photo of natural chemistry and its common issues and principles.

Support Materials
The significant other site (, to be had to all adopters of the textual content, includes:
- 3D natural Animations: hyperlink to chemtube3d to view interactive 3D animations constructed via the author
- extra Chapters: 4 chapters from the 1st variation that don't look within the second
- Errata: Corrections to the ebook because publication
- End-of-Chapter Questions: a number of difficulties to accompany every one chapter
- Figures in PowerPoint: Figures pre-inserted into PowerPoint to be used in lectures and handouts
- difficulties: difficulties to accompany every one bankruptcy from the hot variation of natural Chemistry could be published within the pupil zone of the book's spouse site all year long (April, June, and December 2012)

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Additional info for Organic Chemistry (2nd Edition)

Example text

These hormones are testosterone and oestradiol, the important human male and female sex hormones. Me OH Me Me OH H H H H H O H O muscone ■ A reminder: solid wedgeshaped bonds are coming towards us out of the paper while cross-hatched bonds are going back into the page away from us. HO testosterone oestradiol Some ring structures are much more complicated. The potent poison strychnine is a tangle of interconnecting rings. Interactive structures of testosterone, oestradiol, strychnine, and buckminsterfullerene N H Buckminsterfullerene Buckminsterfullerene is named after the American inventor and architect Richard Buckminster Fuller, who designed the structures known as ‘geodesic domes’.

Try this example—the list of contents from a well-known brand of shower gel, which we are reassuringly told is ‘packed with natural stuff’ (including 10 ‘real’ lemons) and contains ‘100% pure and natural lemon and tea tree essential oils’. It doesn’t all make sense to us, but here is a possible interpretation. ) of this sort of thing. Ingredient aqua Chemical meaning H Purpose H O solvent water sodium laureth sulfate C12H25 O OSO3Na detergent n typically n = 3 O cocamide DEA OH N C11H23 foaming agent OH mainly scent, appeal to customer Citrus medica limonum peel oil α-pinene mainly OH scent, appeal to customer, possibly antiseptic Melaleuca alternifolia leaf oil terpinen-4-ol OH glycerin HO cosolvent; moisturizer; ensures smoothness OH glycerol O cocamidopropyl betaine N H C11H24 O N detergent and anti-electrostatic O sodium chloride control solubility of Na+-based detergents NaCl OH acidifier lactic acid CO2H styrene acrylates copolymer Ph CO2R R = Me or H R n tetrasodium glutamate diacetate m NaO2C CO2Na NaO2C film former N CO2Na chelator, to prevent formation of insoluble scum in hard water CO2Na sodium benzoate preservative 7 8 CHAPTER 1 WHAT IS ORGANIC CHEMISTRY?

The four-membered ring at the heart of the molecule is the β-lactam, which targets the diease-causing bacteria. Medicinal chemists also protect us from the insidious threat of viruses which use the body’s own biochemistry to replicate. Tamiflu is a line of defence against the ever-present danger of a flu epidemic, while ritonivir is one of the most advanced drugs designed to prevent replication of HIV and to slow down or prevent the onset of AIDS. NH2 H H N O H S O H3C HO O CH3 N O O H3C HN CO2H amoxycillin developed by SmithKline Beecham β-lactam antibiotic treatment of bacterial infections H3C O NH2 O N N S CH3 Tamiflu (oseltamivir) invented by Gilead Sciences marketed by Roche O H N N H O N H OH O S N ritonavir (Norvir) Abbott's protease inhibitor treatment for HIV / AIDS The best-selling current drugs are largely designed to address the human body’s own failings.

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